Careers

R&D Associate

Job Title
R&D Associate
Job ID
27490224
Location
Gainesville Area,  FL
Other Location
Description

Mission

The R&D Associate on the Assay Development Preclinical R&D team is responsible for support of the Assay Development team by developing, qualifying and troubleshooting quantitative, semi-quantitative, and qualitative assays in support of research, nonclinical, and clinical programs. 

Reporting Relationship

  • The Research Associate will report directly to the R&D Manager or designee

Duties and Responsibilities

  • Develop and qualify new assay methods in support of IND enabling non-clinical and clinical studies, including in vitro cell-based assays, immunoassays, and molecular assays.
  • Plan strategies for and participate in the development, qualification, and transfer of quantitative and semi-quantitative bioanalytical methods to support product release
  • May assist in preparing technology transfer, assay validation and clinical sample testing at CROs
  • Conduct routine assays and procedures in support of manufacturing activities for generation of viral vectors for animal studies
  • May conduct testing of samples from animal studies, including but not limited to performing dose analysis testing for research studies, developing and troubleshooting routine R&D sample test methods
  • Perform stability testing for critical reagents used for assays in validation phase
  • Plan, execute, and troubleshoot experiments
  • Collect, analyze, record, and summarize data
  • Write and/or review SOPs, technical reports and study reports
  • Maintain relevant laboratory supplies and equipment as needed
  • Present scientific results at appropriate meetings
  • Observe and comply with AGTC’s Employee manual and Safety and Quality manual
  • Knowledge of laboratory safety, OSHA policies, and EPA standards
  • Other duties as assigned.
  • This job description is subject to change at any time

Educational Qualifications

  • A B.S. in biological sciences or related field
  • M.S. with a degree in biological science or related field preferred

Additional Qualifications

  • R&D Associate I: no prior experience, one (1) year preferred
  • R&D Associate II: at least two (2) years of experience
  • R&D Associate III: at least five (5) years of experience, two (2) years of industrial experience in assay development is highly desirable
  • Senior R&D Associate: at least eight (8) years of experience. 
  • The experience for all levels should be in a QC and/or AD environment focused on biologics Advanced proficiency in basic biological laboratory techniques, including ELISA, immunoblot, PCR, mammalian cell culture, and transfection
  • Background in the area of retinal or genetic diseases is desired, with an understanding of AAV biology a plus
  • Ability to design and develop new assay methods with minimal supervision
  • Understanding/working knowledge of Microsoft Word, Excel and PowerPoint
  • Ability to read and extract information from published literature and internal reports is required.
  • Proficiency with SoftMaxPro, GraphPad Prism, JMP, and other common analytical software desired.
  • Detail oriented with time management skills.
  • Proven initiative and demonstrated accountability in a fast-paced environment with high degree of flexibility.
  • Knowledge of techniques such as flow cytometry and immunofluorescence are strongly desired.
  • Broad knowledge of cell assay methods and biochemistry with application to gene therapy (for example, neutralizing antibody assays) is strongly desired.
  • Hands-on laboratory experience in immunology, molecular biology, cell biology, virology or related areas.
  • Highly motivated with the ability to work as a team player, as well as independently.
  • May perform on the job training for other members of R&D
  • Detail oriented with strong written and verbal communication skills

 Physical Requirements

  • Physical demands: (check one)

☒ sedentary (< 10 lbs.)

☐ light work (< 20 lbs.)

☐ medium work (< 50 lbs.)

☐ heavy work (< 100 lbs.)

☐ very heavy work (> 100 lbs.)

 

  • Physical activity: (check all that apply)

☐repetitive motion

☐ balancing

☒stooping

☐lifting

☐climbing

☐kneeling/crouching

☐crawling

☐reaching

☒standing

 

☒ typing/grasping

☒walking

☐pushing/pulling

☒hearing

 

  • Visual acuity: reading, writing, preparing/analyzing data
  • Working conditions: indoor office environment and lab area

 Supervisor Responsibilities

  • This position does not require previous supervisory experience

Option 1: Create a New Profile

Visionary science for life changing cures.