Join Our Team - OnKure, Inc.
people in a business meeting

We are building a skilled and dedicated team of experienced life science leaders who are driven by our common mission: to develop differentiated therapies to improve the lives of patients. We work with a sense of urgency and purpose, foster a collaborative culture that prioritizes cross-functional learning and reward our employees with highly competitive benefits.

Located in Boulder, Colorado, which was recently awarded the best place to live by U.S. News, OnKure is actively seeking to hire ambitious team players to expand our growing organization.


Research Scientist / Senior Research Scientist, Medicinal Chemistry

Job Title
Research Scientist / Senior Research Scientist, Medicinal Chemistry
Job ID
Boulder,  CO
Other Location
OnKure’s Drug Discovery team has immediate openings for Medicinal Chemists who will work in a highly interactive, fast-paced, team environment to develop clinical drug candidates. 

What You Will Achieve:
​​You will make key contributions to the design and syntheses of small molecule-derived drugs.

How You Will Achieve It:
Using your synthetic chemistry knowledge, collaborate with team members to solve medicinal chemistry challenges and deliver on project team goals with a high level of productivity.  

Preferred Experience and Qualifications:
  • M.S., Ph.D., or B.S. plus equivalent experience in chemistry with a focus on synthetic organic chemistry
  • Experience in small molecule drug discovery in a biotechnology or pharmaceutical setting and a M.S. with 5+ years’ experience or Ph.D. with 2+ years’ experience 
  • Expertise in methodology development and problem solving in multistep syntheses
  • Drive the project by designing and synthesizing new analogs that directly address project goals
About OnKure:
OnKure, Inc. is a private biotech company, based in Boulder, Colorado. The company was founded and is led by several scientific leaders from Array BioPharma, another Boulder-based company. Our mission is to create novel, high quality drugs to provide meaningful therapy for cancer patients. Our near-term goals are to advance our clinical stage drug, OKI-179, into several Phase 2 clinical trials, build a state-of-the-art drug discovery group and establish a robust pipeline of projects and development candidates.

Our Boulder facilities feature modern offices, and new laboratories are under construction.  With the mountains at our doorstep, great schools, cultural and unparalleled outdoor activities, Boulder is the No. 1 place to live out of the 150 most populous metro areas in the U.S. for the second year in a row! 

To attract the very best talent, OnKure offers a generous compensation and benefits package that includes competitive pay, performance-based bonus opportunities, stock options, insurance coverage (health, dental, life, and disability), self-managed paid time off, and a 401(k) plan with company match. We operate on a flexible schedule that allows a combination of both in-office and home-based work.

Annual compensation range for this role, based on experience is $100,000-$135,000.

OnKure is an equal opportunity employer and welcomes all job applicants. All qualified applicants will receive consideration for employment without discrimination based on race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability, or any other protected factors.

Option 1: Create a New Profile