XenoSTART, the preclinical division of START is a translational research organization focused on creating relevant preclinical cancer models.  Our xenograft models represent each cancer type and disease stage and are established from patients at our domestic and international cancer centers. The XenoSTART Patient-Derived Xenograft (XPDX) platform includes over 2,500 models annotated with each donor patient’s cancer treatment and outcome data and characterized using IHC, DNA/RNA sequencing, and relevant in vivo drug efficacy.

​​Our XPDX models are clinically annotated and include patient treatment history and outcome and are characterized through genomic profiling, histologic analysis, and in vivo drug sensitivity to relevant standards of care. These models may be utilized in the following manner:

• ​In vivo PK/PD and efficacy studies
• In vivo efficacy panel screens (indication or target focused)
• In licensing of models for internal studies
• Custom model development
• Orthotopic and radiotherapy studies
• Ex vivo and organoid studies

The Husbandry Technician I plays a vital role in the daily care and welfare of laboratory animals within the START Preclinical Group (XenoSTART). Under the direct supervision of the Manager, Vivarium Operations, the technician is responsible for performing routine husbandry, animal handling, facility maintenance, and ensuring compliance with regulatory and institutional animal care standards. This entry-level position is ideal for candidates seeking a career in biomedical research and animal care.

 Essential Responsibilities:

• Provide daily husbandry care to laboratory animals, including feeding, watering, cage cleaning, and environmental enrichment in accordance with standard operating procedures (SOPs) and IACUC regulations.
• Handle small animals (e.g., rodents) for general care, health observations, and other assigned procedures.
• Monitor animal health and report abnormal clinical signs or concerns to attending veterinary or supervisory staff promptly.
• Maintain cleanliness and proper sanitation of the animal facility, including cages, racks, bottles, and work areas.
• Perform routine sterilization procedures using autoclaves or other appropriate equipment.
• Carry out humane euthanasia procedures following approved protocols and guidelines.
• Assist research and technical staff in laboratory procedures and study preparation.
• Maintain accurate records of animal care, room conditions, and husbandry activities in both written and electronic formats.
• Support inventory management by monitoring and restocking supplies such as bedding, feed, and cleaning materials.
• Participate in training sessions, team meetings, and study briefings to stay informed on current protocols and safety practices.
• Ensure all activities comply with institutional policies, AAALAC standards, and federal animal welfare regulations.
• Perform additional related duties or responsibilities as assigned by supervisory personnel.

Qualifications:

Required:

• High school diploma or equivalent.
• Ability to follow detailed instructions, SOPs, and animal care protocols.
• Strong observational and record-keeping skills.
• Ability to work effectively in a fast-paced, team-oriented environment.
• Physical capability to lift over 40 pounds, stand for extended periods, and perform repetitive tasks.

Preferred:

• Prior experience in animal care, laboratory animal research, or a veterinary setting.
• Familiarity with animal welfare standards and regulatory compliance (e.g., IACUC, AAALAC).
• Interest in pursuing a career in laboratory animal science or biomedical research.

We value our employees’ time and efforts. Our commitment to your success is enhanced by a competitive compensation, depending on experience, and an extensive benefits package including:

• Comprehensive health coverage: Medical, dental, and vision insurance provided
• Robust retirement planning: 401(k) plan available with employer matching
• Financial security: Life and disability insurance for added protection
• Flexible financial options: Health savings and flexible spending accounts offered
• Well-being and work-life balance: Paid time off, flexible schedule, and remote work choices provided

Plus, we work to maintain the best environment for our employees, where people can learn and grow with the company. We strive to provide a collaborative, creative environment where everyone feels encouraged to contribute to our processes, decisions, planning, and culture.

 More about The START Center for Cancer Research

Deeply rooted in community oncology centers globally, The START Center for Cancer Research provides access to specialized preclinical and early-phase clinical trials of novel anti-cancer agents. START clinical trial sites have conducted more than a thousand early-phase clinical trials, including for 43 therapies that were approved by the FDA. START represents the world’s largest roster of Principal Investigators (PIs) across its eight clinical trial sites. Committed to accelerating passage from trials to treatments, START delivers hope to patients, families, and physicians around the world. Learn more at STARTresearch.com.

 Ready to be part of a team changing the future of cancer treatment?

Join us in our mission to conquer cancer, one clinical trial at a time. Your expertise and dedication can help us bring hope and healing to patients worldwide. Please submit your application online.

 We are an equal opportunity employer that welcomes and encourages diversity in the workplace. We do not discriminate on the basis of race, color, religion, marital status, age, national origin, ancestry, physical or mental disability, medical condition, pregnancy, genetic information, gender, sexual orientation, gender identity or expression, veteran status, or any other status protected under federal, state, or local law.