Scientific Lead of Technical Operations
- Job Title
- Scientific Lead of Technical Operations
- Job ID
- 27736171
- Location
- San Antonio, TX, 78229
- Other Location
- Description
-
XenoSTART, the preclinical division of START is a translational research organization focused on creating relevant preclinical cancer models. Our xenograft models represent each cancer type and disease stage and are established from patients at our domestic and international cancer centers. The XenoSTART Patient-Derived Xenograft (XPDX) platform includes over 2,500 models annotated with each donor patient’s cancer treatment and outcome data and characterized using IHC, DNA/RNA sequencing, and relevant in vivo drug efficacy.
Our XPDX models are clinically annotated and include patient treatment history and outcome and are characterized through genomic profiling, histologic analysis, and in vivo drug sensitivity to relevant standards of care. These models may be utilized in the following manner:
- In vivo PK/PD and efficacy studies
- In vivo efficacy panel screens (indication or target focused)
- In licensing of models for internal studies
- Custom model development
- Orthotopic and radiotherapy studies
- Ex vivo and organoid studies
We are hiring a Scientific Lead of Technical Operations, at our XenoSTART site in San Antonio, TX. This is an on-site position.
The position is the primary instructor for technical training programs for In Vivo research personnel. Determines training objectives by conducting analysis of overall needs and specific skill or knowledge gaps. Manages and improves the development of training programs and materials including outlines, text, handouts, virtual and hands on exercises, and training evaluations. Establishes processes to monitor results and collect feedback on training instructors to determine effectiveness and identify areas for improvement. Assesses and manages any contractors utilized to deliver specialized training.
Essential Responsibilities:- Design and develop educational materials, training, and onboarding curriculum related to In Vivo Research techniques.
- Provide leadership and collaborate with the management team and Subject Matter Experts (SMEs) on content development and delivery of training.
- Develop and implement standard training and onboarding procedures for new and current staff, ensuring all job roles in the departments have completed necessary training and demonstrate competencies consistent with duties outlined in their respective job description.
- Develop, refine, and implement Standard Operating Procedures (SOPs) for Core Operations Departments and assist as needed with SOPs in other areas.
- Facilitate research-related on-boarding activities for new staff.
- Instruct In Vivo research personnel on SOPs, policies, regulatory requirements, and best practices.
- Lead the development of assessment tools and mechanisms to evaluate the effectiveness of the training programs and recommend improvements.
Required Knowledge, Skills & Abilities:- Bachelor’s degree required in relevant field (such as ethics, education, science)
- 5 years of experience in research administration or related compliance experience (e.g., IACUC, IBC, IRB).
- 3 years of experience in a CRO environment or pharma/biotech industry and working understanding of pharmacology principles and oncology drug development programs in the pharmaceutical industry.
- Familiarity with research ethics, regulatory requirements, and best practices in responsible conduct of preclinical oncology research.
- Deep knowledge of preclinical oncology research techniques including but not limited to model development and execution of PK/PD/Efficacy studies in patient derived xenograft (PDX) and cell-derived xenograft (CDX) platforms.
- Experience in curriculum development and educational program design.
Preferred Knowledge, Skills & Abilities:- Deep hands-on proficiency with common in vivo technical procedures in mice (compound administration, sample collection, surgery).
- Ability to work quickly, effectively, and productively in a team-oriented environment.
- Understanding of global animal welfare regulations and standards.
Best-in-Class Benefits and Perks
We value our employees’ time and efforts. Our commitment to your success is enhanced by a competitive compensation, depending on experience, and an extensive benefits package including:- Comprehensive health coverage: Medical, dental, and vision insurance provided
- Robust retirement planning: 401(k) plan available with employer matching
- Financial security: Life and disability insurance for added protection
- Flexible financial options: Health savings and flexible spending accounts offered
- Well-being and work-life balance: Paid time off, flexible schedule, and remote work choices provided
- Plus, we work to maintain the best environment for our employees, where people can learn and grow with the company. We strive to provide a collaborative, creative environment where everyone feels encouraged to contribute to our processes, decisions, planning, and culture.
More about The START Center for Cancer Research
Deeply rooted in community oncology centers globally, The START Center for Cancer Research provides access to specialized preclinical and early-phase clinical trials of novel anti-cancer agents. START clinical trial sites have conducted more than a thousand early-phase clinical trials, including for 43 therapies that were approved by the FDA. START represents the world’s largest roster of Principal Investigators (PIs) across its eight clinical trial sites. Committed to accelerating passage from trials to treatments, START delivers hope to patients, families, and physicians around the world. Learn more at STARTresearch.com.
Ready to be part of a team changing the future of cancer treatment?
Join us in our mission to conquer cancer, one clinical trial at a time. Your expertise and dedication can help us bring hope and healing to patients worldwide. Please submit your application online.
We are an equal opportunity employer that welcomes and encourages diversity in the workplace. We do not discriminate on the basis of race, color, religion, marital status, age, national origin, ancestry, physical or mental disability, medical condition, pregnancy, genetic information, gender, sexual orientation, gender identity or expression, veteran status, or any other status protected under federal, state, or local law.
